To get started, select a dataset and analytic mode below:


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Functional CpG-Gene pairs:

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Methylation states (DM value matrix):

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DM < 0: hypomethylated; DM > 0: hypermethylated; DM = 0: normally methylated

Please select a gene and a CpG site on the left panel

Please load a data set in the first tab

Figure 1: Histogram showing the mixture model of the selected CpG probe. The X axis reprsents the betal values of DNA methylation and the Y axis represents the population density at each methylation level.


Figure 2: Violin plot showing the expression levels of the selected gene for samples in each mixture component in Figure 1.


Figure 3: Scatter plot showing the correlation between DNA methylation and gene expression.

Use this page to explore the differentially methylated genes that are predictive of patient survival

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The patient survival data are not avalible for this dataset

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To generate a survival graph, please select a gene and a CpG site in the left panel


Figure 1: Histogram showing the mixture model of the selected CpG probe.

Figure 2: Kaplan-Meier survival curve showing the patients in different mixtures

Use this page to perform functional enrichment analysis for the differentially methylated genes

Please load a data set in the first tab
Pathway enrichment analysis is currently only supported for the Regular and the Enhancer mode
  • For pathway analysis for miRNAs, please use miRNet
  • For pathway analysis for lncRNAs, please use ncFANs
  • Performing the analysis can take up to a few minutes, please be patient ...
    Performing analysis...



    Download Results

    Please load a data set in the first tab
    Please select a gene name in the left panel


    Note: Generating the graph can take up to a few minutes, please be patient...

    Generating graph...